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Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery
Nicholas J. Brandon
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Description for Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System: From Biology to Drug Discovery
Hardcover. This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Editor(s): Brandon, Nicholas J.; West, Anthony R. Series: Wiley Series in Drug Discovery and Development. Num Pages: 400 pages, illustrations. BIC Classification: MBGR; MFG; PN; PSBZ. Category: (P) Professional & Vocational. Dimension: 243 x 162 x 26. Weight in Grams: 726.
This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.
This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia and industry describe these, then focus on the areas of greatest scientific and medical interest to provide more detailed coverage. Therapeutic and drug discovery applications are covered for diseases including Alzheimer's, Parkinson's, schizophrenia, erectile dysfunction, and spinal cord injuries. There is also a chapter on drug discovery tools such as in vitro assays and X-ray structures for medicinal chemistry studies.
Product Details
Format
Hardback
Publication date
2014
Publisher
John Wiley & Sons Inc United Kingdom
Number of pages
384
Condition
New
Series
Wiley Series in Drug Discovery and Development
Number of Pages
400
Place of Publication
New York, United States
ISBN
9780470566688
SKU
V9780470566688
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About Nicholas J. Brandon
NICHOLAS BRANDON works at AstraZeneca within the Neuroscience Innovative Medicines Group. He has spent his career in drug discovery with a strong interest in developing phosphodiesterase inhibitors for neuropsychiatric disorders and understanding the basic mechanisms of phosphodiesterase function. ANTHONY WEST is an Associate Professor in the Department of Neuroscience at Rosalind Franklin University. He has studied PDE function ... Read more
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