Cytokines and Pain
Watkins, Linda R.; Maier, Steven F.
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Description for Cytokines and Pain
Paperback. Series: Progress in Inflammation Research. Num Pages: 240 pages, biography. BIC Classification: MJC; MJCM. Category: (G) General (US: Trade). Dimension: 235 x 155 x 13. Weight in Grams: 379.
Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation ... Read more
Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation ... Read more
Product Details
Format
Paperback
Publication date
1998
Publisher
Springer Basel Switzerland
Number of pages
240
Condition
New
Series
Progress in Inflammation Research
Number of Pages
232
Place of Publication
Basel, Switzerland
ISBN
9783034897563
SKU
V9783034897563
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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