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Drug Metabolism and Transport
Lawrence H. . Ed(S): Lash
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Description for Drug Metabolism and Transport
Paperback. Editor(s): Lash, Lawrence H. Series: Methods in Pharmacology and Toxicology. Num Pages: 398 pages, 110 black & white illustrations, biography. BIC Classification: MQP. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 22. Weight in Grams: 586.
A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.
A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.
Product Details
Format
Paperback
Publication date
2010
Publisher
Humana Press Inc. United States
Number of pages
398
Condition
New
Series
Methods in Pharmacology and Toxicology
Number of Pages
388
Place of Publication
Totowa, NJ, United States
ISBN
9781617374944
SKU
V9781617374944
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Drug Metabolism and Transport
"With the diverse subject matter and the wealth of information on techniques and research strategies there is likely to be something in this book to interest those from PhD students to more experienced researchers." -Newsletter of the British Toxicological Society