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Farnesyltransferase Inhibitors in Cancer Therapy
. Ed(S): Sebti, Said M.; Hamilton, Andrew D.
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Description for Farnesyltransferase Inhibitors in Cancer Therapy
Paperback. Editor(s): Sebti, Said M.; Hamilton, Andrew D. Series: Cancer Drug Discovery and Development. Num Pages: 280 pages, biography. BIC Classification: MJCL; TDCW. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 16. Weight in Grams: 566.
Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific ... Read more
Cutting-edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other cytotoxic agents, such as gemcitabine, cisplatin, and taxanes. Illuminating and richly detailed, Farnesyltransferase Inhibitors in Cancer Therapy constitutes today's standard reference for the pathbreaking use of FTIs and GGTIs in anticancer therapy and offers basic and clinical investigators a comprehensive treatment of the scientific ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Humana Press Inc. United States
Number of pages
280
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
280
Place of Publication
Totowa, NJ, United States
ISBN
9781468496062
SKU
V9781468496062
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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