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Genomic Disorders: The Genomic Basis of Disease
. Ed(S): Lupski, James R.; Stankiewicz, Pawel T.
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Description for Genomic Disorders: The Genomic Basis of Disease
paperback. Editor(s): Lupski, James R.; Stankiewicz, Pawel T. Num Pages: 426 pages, 111 black & white illustrations, 1 colour illustrations, biography. BIC Classification: MMF. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 23. Weight in Grams: 846.
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
A grand summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
Product Details
Format
Paperback
Publication date
2010
Publisher
Springer/Sci-Tech/Trade United States
Number of pages
426
Condition
New
Number of Pages
426
Place of Publication
Totowa, NJ, United States
ISBN
9781617376429
SKU
V9781617376429
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Genomic Disorders: The Genomic Basis of Disease
"...an attempt to bridge the gap between genomic technology and clinical applications of genomic knowledge." -Doody's Book Review, Weighted Numerical Score: 84 - 3 stars "...a unique contribution in a very specialized field." -Doody's Book Review, Weighted Numerical Score: 84 - 3 stars