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Histone Deacetylases
Eric . Ed(S): Verdin
€ 243.33
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Description for Histone Deacetylases
Paperback. Editor(s): Verdin, Eric. Series: Cancer Drug Discovery and Development. Num Pages: 354 pages, 62 black & white illustrations, 1 colour illustrations, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 18. Weight in Grams: 474.
A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.
A panel of leading investigators summarizes and synthesizes the new discoveries in the rapidly evolving field of histone acetylation as a key regulatory mechanism for gene expression. The authors describe what has been learned about these proteins, including the identification of the enzymes, the elucidation of the enzymatic mechanisms of action, and the identification of their substrates and their partners. They also review the structures that have been solved for a number of enzymes-both alone and in complex with small molecule inhibitors-and the biological roles of the several histone deacetylases (HDAC) genes that have been knocked out in mice.
Product Details
Format
Paperback
Publication date
2010
Publisher
Humana Press Inc. United States
Number of pages
354
Condition
New
Series
Cancer Drug Discovery and Development
Number of Pages
352
Place of Publication
Totowa, NJ, United States
ISBN
9781617376023
SKU
V9781617376023
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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