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. Ed(S): Lecea, Luis de (The Scripps Research Institute La Jolla); Sutcliffe, J. Gregor (The Scripps Research Institute La Jolla) - Hypocretins - 9780387250007 - V9780387250007
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Hypocretins

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Description for Hypocretins Hardback. The hypocretins (orexins) are an identified (1998) peptide family comprised of two peptides, hypocretin-1 and hypocretin-2. They are involved in circadian rhythms, metabolism, hormone secretion, body temperature, appetite, cardiovascular functions (blood pressure), and sleep abnormalities (narcolepsy and cataplexy). Editor(s): Lecea, Luis de (The Scripps Research Institute La Jolla); Sutcliffe, J. Gregor (The Scripps Research Institute La Jolla). Num Pages: 441 pages, 11 black & white tables, biography. BIC Classification: MJN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 25. Weight in Grams: 945.
The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with “wide awake” EEG patterns and EMG suppression. The first report linking REM sleep to a pathology occurred in 1961 and a clear association of sleep onset REM periods, cataplexy, hypnagogic hallucinations and sleep paralysis was ... Read more

Product Details

Format
Hardback
Publication date
2005
Publisher
Springer-Verlag New York Inc. United States
Number of pages
441
Condition
New
Number of Pages
441
Place of Publication
New York, NY, United States
ISBN
9780387250007
SKU
V9780387250007
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

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