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Ramanathan - Mass Spectrometry in Drug Metabolism and Pharmacokinetics - 9780471751588 - V9780471751588
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Mass Spectrometry in Drug Metabolism and Pharmacokinetics

€ 171.84
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Description for Mass Spectrometry in Drug Metabolism and Pharmacokinetics Hardcover. This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. Editor(s): Ramanathan, Ragu. Num Pages: 390 pages, Illustrations. BIC Classification: MMG; PNFS. Category: (P) Professional & Vocational. Dimension: 242 x 167 x 24. Weight in Grams: 670.
This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body, the book s focuses on the use of LC/MS and MALDI-MS. This is a valuable reference for scientists in the pharmaceutical industry, medicine, academia, and even those working in homeland defense.

Product Details

Format
Hardback
Publication date
2008
Publisher
John Wiley and Sons Ltd United Kingdom
Number of pages
390
Condition
New
Number of Pages
408
Place of Publication
New York, United States
ISBN
9780471751588
SKU
V9780471751588
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-50

About Ramanathan
Ragu Ramanathan received a B.Sc. in Chemistry from the University of Southern Mississippi and a Ph.D. in Physical Chemistry/Mass Spectrometry from the University of Florida. His graduate research focused on coupling of electrospray ionization (ESI) to Fourier transform ion cyclotron resonance (FTICR) mass spectrometer. After spending three years as a postdoctoral research fellow with Professor Michael L. Gross at the Washington University, St. Louis, Missouri, Dr. Ramanathan managed the Center for Advanced Mass Spectrometry at the Analytical Bio-Chemistry Laboratories, Columbia, Missouri. In 1998, Dr. Ramanathan joined Schering-Plough Research Institute’s (SPRI) Drug Metabolism and Pharmacokinetics (DMPK) Department and completed his tenure as a senior principal scientist in 2008. While at SPRI, Dr. Ramanathan was involved in the application of LC–MS for profiling and characterization of metabolites of drug candidates in the preclinical development and clinical stages. Dr. Ramanathan was with Pfizer Global Research and Development from 1999 to 2002 as a group leader of the Ann Arbor site biotransformation group. Dr. Ramanathan is currently an associate director at the Bristol-Myers Squibb, Co. and is responsible for elucidating biotransformation pathways of development drug candidates. Dr. Ramanathan’s accomplishments include 35 peer-reviewed papers, 10 book chapters, and over 60 oral/poster presentations. He also served as a chairperson for the North Jersey ACS Mass Spectrometry Discussion Group and as a chairman for DMPK sessions of the American Society for Mass Spectrometry and Eastern Analytical Symposium meetings.

Reviews for Mass Spectrometry in Drug Metabolism and Pharmacokinetics
“All in all, the book delivers on its promises to introduce and review the current art of mass spectrometry for the related disciplines of drug metabolism and pharmacokinetics. I highly recommend it.” (JACS Book Reviews, June 2009) “In comparison to other books on mass spectrometry, this one not only provides both the basic and latest knowledge in mass spectrometry, but integrates the theory with applications to drug metabolism and pharmacokinetics.” (Doody's, April 2009) "Mass Spectrometry in Drug Metabolism and Pharmacokinetics is a valuable and interesting resource for a broad readership, including scientists starting to work in DMPK as well as undergraduate and graduate students getting involved in drug discovery and characterization by means of MS. A wealth of information is provided and all of the contributing authors have done an excellent job in explaining and outlining particular aspects of MS-based tools in DMPK ... the book is highly recommended reading." (Journal of the American Society for Mass Spectrometry, March 2009)

Goodreads reviews for Mass Spectrometry in Drug Metabolism and Pharmacokinetics


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