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Molecular Analysis of DNA Rearrangements in the Immune System
. Ed(S): Jessberger, Rolf; Lieber, Michael R.
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Description for Molecular Analysis of DNA Rearrangements in the Immune System
paperback. Editor(s): Jessberger, Rolf; Lieber, Michael R. Series: Current Topics in Microbiology and Immunology. Num Pages: 233 pages, 13 black & white tables, biography. BIC Classification: MJCM; PSB; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 13. Weight in Grams: 373.
The vertebrate immune system is distinctive among defense systems of multicellular organisms. In addition to nonspecific immunity, it generates a randomized array of millions of antigen receptors (immunoglobulins and T-cell receptors). A subset of these receptors are critical for binding to invading microbes or biochemicals from them to tag the microbes for elimination. Three site-directed DNA modification processes are critical to this process in vertebrates. V(D)J recombination generates the array of exons that encode the antigen binding pockets. Recent work summarized in this volume describes the dissection of this process at the biochemical level. The mechanism of the reaction is ... Read more
The vertebrate immune system is distinctive among defense systems of multicellular organisms. In addition to nonspecific immunity, it generates a randomized array of millions of antigen receptors (immunoglobulins and T-cell receptors). A subset of these receptors are critical for binding to invading microbes or biochemicals from them to tag the microbes for elimination. Three site-directed DNA modification processes are critical to this process in vertebrates. V(D)J recombination generates the array of exons that encode the antigen binding pockets. Recent work summarized in this volume describes the dissection of this process at the biochemical level. The mechanism of the reaction is ... Read more
Product Details
Format
Paperback
Publication date
2012
Publisher
Springer Germany
Number of pages
233
Condition
New
Series
Current Topics in Microbiology and Immunology
Number of Pages
224
Place of Publication
Berlin, Germany
ISBN
9783642501425
SKU
V9783642501425
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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