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Molecular Neurosurgery with Targeted Toxins
. Ed(S): Wiley, Ronald G.; Lappi, Douglas
€ 229.05
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Description for Molecular Neurosurgery with Targeted Toxins
Hardback. Gives a treatment of the highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals. This book explains the theory and techniques of using targeted toxins experimentally. Editor(s): Wiley, Ronald G.; Lappi, Douglas. Num Pages: 312 pages, biography. Category: (G) General (US: Trade); (P) Professional & Vocational; (U) Tertiary Education (US: College). Dimension: 235 x 155 x 21. Weight in Grams: 654.
Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and ... Read more
Pioneers and leading researchers explain the theory and techniques of using targeted toxins experimentally. The highly successful use of the 192 IgG-saporin and ME20.4-saporin immunotoxins to lesion the cholinergic basal forebrain in order to model the behavior, anatomy, physiology, and pharmacology of Alzheimer's disease in animals is treated in detail to give a potential user the knowledge to comfortably use the techniques involved. The uses of important new lesioning agents such as anti-DBH-saporin immunotoxin to make remarkably selective lesions of catecholaminergic neurons, hypocretin-saporin that can produce narcoleptic animals, and other saporin conjugates, such as neuropeptide-saporin conjugates for pain research and ... Read more
Product Details
Format
Hardback
Publication date
2005
Publisher
Humana Press Inc. United States
Number of pages
312
Condition
New
Number of Pages
312
Place of Publication
Totowa, NJ, United States
ISBN
9781588291998
SKU
V9781588291998
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Molecular Neurosurgery with Targeted Toxins
"...a good purchase for most neuroscience and neurology libraries." - Doody's Health Science Book Review Journal