Peptidomimetics Protocols
Wieslaw M. . Ed(S): Kazmierski
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Description for Peptidomimetics Protocols
Paperback. Editor(s): Kazmierski, Wieslaw M. Series: Methods in Molecular Medicine. Num Pages: 549 pages, biography. BIC Classification: MF. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 32. Weight in Grams: 841.
Many physiologically important receptors and enzymes are regulated by their endogenous ligands and inhibitors. Nature chose to utilize these p- tides as chemical switches since they can be efficiently synthesized and - graded in cells, thus providing an immediate response to a fast changing environment. Such properties, so critical in cell survival, make peptides less than ideal drug candidates. Other frequently desired properties in drug m- ecules include oral bioavailability, the ability to cross membranes, including the blood-brain barrier, and sufficient stability for administration 1-2 times a day. In spite of these obstacles, some natural peptides and proteins are ind- ... Read more
Many physiologically important receptors and enzymes are regulated by their endogenous ligands and inhibitors. Nature chose to utilize these p- tides as chemical switches since they can be efficiently synthesized and - graded in cells, thus providing an immediate response to a fast changing environment. Such properties, so critical in cell survival, make peptides less than ideal drug candidates. Other frequently desired properties in drug m- ecules include oral bioavailability, the ability to cross membranes, including the blood-brain barrier, and sufficient stability for administration 1-2 times a day. In spite of these obstacles, some natural peptides and proteins are ind- ... Read more
Product Details
Format
Paperback
Publication date
2010
Publisher
Humana Press Inc. United States
Number of pages
549
Condition
New
Series
Methods in Molecular Medicine
Number of Pages
549
Place of Publication
Totowa, NJ, United States
ISBN
9781617370595
SKU
V9781617370595
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Peptidomimetics Protocols
"The editor has assembled an interesting collection of synthetic methods for preparing peptidomimetics. . .This book will clearly be of value to those who are interested in synthesizing nonpeptidic analogues of small peptide ligands."-Journal of Medicinal Chemistry "the editor does an excellent job of bringing together a variety of different chemical syntheses that are relevant to peptide, ... Read more