Protein Misfolding and Disease
. Ed(S): Bross, Peter; Bross, Peter
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Description for Protein Misfolding and Disease
Hardback. Provides a review of the thinking about the molecular processes underlying conformational diseases, combined with a set of biochemical, genomic cellular, and chemical laboratory techniques for studying their genesis and pathologies. This title applies their carefully refined methods to a variety of metabolic and neurodegenerative disorders. Editor(s): Bross, Peter; Bross, Peter. Series: Methods in Molecular Biology. Num Pages: 318 pages, biography. BIC Classification: MMFC. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 20. Weight in Grams: 653.
For decades it has been known that structured conformations are important for the proper functioning of most cellular proteins. However, appreciation that protein folding to the functional conformations as well as the structural maintenance of protein molecules are very complex processes has only emerged during the last ten years. The intimate interplay uncovered by this scientific development led us to realize that perturbations of the protein folding process and disturbances of conformational maintenance are major disease mechanisms. This development has given rise to the concept of conformational diseases and the broader signature of protein folding diseases, comprising diseases in which ... Read more
For decades it has been known that structured conformations are important for the proper functioning of most cellular proteins. However, appreciation that protein folding to the functional conformations as well as the structural maintenance of protein molecules are very complex processes has only emerged during the last ten years. The intimate interplay uncovered by this scientific development led us to realize that perturbations of the protein folding process and disturbances of conformational maintenance are major disease mechanisms. This development has given rise to the concept of conformational diseases and the broader signature of protein folding diseases, comprising diseases in which ... Read more
Product Details
Format
Hardback
Publication date
2003
Publisher
Humana Press Inc. United States
Number of pages
318
Condition
New
Series
Methods in Molecular Biology
Number of Pages
318
Place of Publication
Totowa, NJ, United States
ISBN
9781588290656
SKU
V9781588290656
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Protein Misfolding and Disease
"...a very sound book that provides a solid background in conformational disease and presents the reader with helpful experimental protocols for studying protein folding folding and misfolding." - Pharmaceutical Research "...this book will be a very useful took for specialists in protein chemistry, molecular biology and basic medicine, and also for teachers and their students studying ... Read more