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Proteopathic Seeds and Neurodegenerative Diseases
. Ed(S): Jucker, Mathias; Christen, Yves
€ 181.01
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Description for Proteopathic Seeds and Neurodegenerative Diseases
Hardback. This book details the latest research on prion diseases and presents developing therapies. It includes contributions from Nobel Laureates Eric Kandel and Stanley Prusiner. Editor(s): Jucker, Mathias; Christen, Yves. Series: Research and Perspectives in Alzheimer's Disease. Num Pages: 168 pages, 4 black & white tables, biography. BIC Classification: MMG; PSAN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 15. Weight in Grams: 421.
The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer’s disease, increasingly implicates the conversion of disease-specific proteins into an aggregate-prone b-sheet-rich state as the prime mover of the neurodegenerative process. This prion-like corruptive protein templating or seeding now characterizes such clinically and etiologically diverse neurological disorders as Alzheimer´s disease, Parkinson’s disease, Huntington’s disease, ... Read more
The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer’s disease, increasingly implicates the conversion of disease-specific proteins into an aggregate-prone b-sheet-rich state as the prime mover of the neurodegenerative process. This prion-like corruptive protein templating or seeding now characterizes such clinically and etiologically diverse neurological disorders as Alzheimer´s disease, Parkinson’s disease, Huntington’s disease, ... Read more
Product Details
Format
Hardback
Publication date
2013
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
168
Condition
New
Series
Research and Perspectives in Alzheimer's Disease
Number of Pages
156
Place of Publication
Berlin, Germany
ISBN
9783642354908
SKU
V9783642354908
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Proteopathic Seeds and Neurodegenerative Diseases
"This is a current comprehensive text of the biochemical mechanisms of gene and protein expression encountered in Alzheimer's, Parkinson's, ALS, MS, prion disorders, and other degenerative diseases. ... Neurologists, neurophysiologists, biochemists, graduate students, postdocs, and anyone in drug development will find it very useful in their work." (Joseph J. Grenier, Amazon.com, January, 2016)