The Design and Analysis of Sequential Clinical Trials
John W Whitehead
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Description for The Design and Analysis of Sequential Clinical Trials
Hardcover. In sequential clinical trials, data from patients treated at the beginning of a trial can be analyzed while the trial is still in progress and subsequent patients can be recruited. This analysis provides stopping rules whereby the number of patients involved can be limited without affecting the results. Num Pages: 328 pages, Illustrations. BIC Classification: MBGR; MBNS. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 241 x 163 x 23. Weight in Grams: 618.
This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.
This book details all aspects of sequential clinical trials from preliminary planning, through the monitoring of the trial, to the final analysis of the results. Emphasis is placed on the triangular test and other procedures based on straight line stopping boundaries. These methods allow for frequent or occasional interim analyses and permit the analysis of a wide variety of patient responses. Alternative procedures are also covered in detail, and these include -spending function methods, repeated confidence intervals and Bayesian approaches to sequential clinical trials.
Product Details
Format
Hardback
Publication date
1997
Publisher
John Wiley and Sons Ltd United Kingdom
Number of pages
328
Condition
New
Number of Pages
328
Place of Publication
New York, United States
ISBN
9780471975502
SKU
V9780471975502
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-50
About John W Whitehead
John Whitehead is the author of The Design and Analysis of Sequential Clinical Trials, Revised, 2nd Edition, published by Wiley.
Reviews for The Design and Analysis of Sequential Clinical Trials
"...This book is clear, it provides many details and is well written..." (Statistical Methods in Medical Research, No.11, 2002)