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The Inflammasomes
. Ed(S): Couillin, Isabelle; Petrilli, Virginie; Martinon, Fabio
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Description for The Inflammasomes
Paperback. Including a range of contributions from numerous leading international experts in the field, this book provides an extensive overview of the current knowledge of inflammasome biology as well as analyzing the role they play in both health and disease. Editor(s): Couillin, Isabelle; Petrilli, Virginie; Martinon, Fabio. Series: Progress in Inflammation Research. Num Pages: 240 pages, biography. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 15. Weight in Grams: 373.
The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions ... Read more
The inflammasome was first described in 2002 as a molecular complex activating proinflammatory caspases and therefore regulating the maturation and biological activities of cytokines such as IL-1 and IL-18. This finding was substantiated by the identification of several mutations in the cias1 gene, encoding the human NLRP3 protein, responsible for several autoinflammatory disorders such as the Muckle Wells syndrome. Since, the interest for this complex has constantly increased and several inflammasome complexes with different specificities have been described. These inflammasomes sense a wide variety of pathogens and danger signals and are key players in the inflammatory response. With the contributions ... Read more
Product Details
Format
Paperback
Publication date
2013
Publisher
Springer Basel Switzerland
Number of pages
240
Condition
New
Series
Progress in Inflammation Research
Number of Pages
226
Place of Publication
, Switzerland
ISBN
9783034803434
SKU
V9783034803434
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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