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Tumor Angiogenesis
. Ed(S): Marme, Dieter; Fusenig, N. E.
€ 394.54
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Description for Tumor Angiogenesis
Hardback. Part 1 of this book describes the basic mechanisms tumor angiogenesis. Part 2 reviews the efforts made to validate new targets and to show efficacy in animals. Part 3 is devoted to the clinical development of the novel anti-angiogenic drugs and their use. Editor(s): Marme, Dieter; Fusenig, N. E. Num Pages: 845 pages, 72 colour tables, biography. BIC Classification: MJCL. Category: (P) Professional & Vocational. Dimension: 279 x 210 x 43. Weight in Grams: 1905.
Preface Tumor development and progression occur as a result of cumulative acquisition of genetic alterations affecting oncogenes and tumor suppressor genes. As a consequence of these alterations the arising tumor gains some fatal properties such as increased cell proliferation and decreased apoptosis, resulting in a net accumulation of tra- formed cells. Once a critical volume is achieved, lack of oxygen and nutrients limits further growth. To overcome this obstacle, the tumor cells initiate a program focused on the formation of new blood vessels within the host tissue. This process is termed tumor angiogenesis and contributes to the progression of most ... Read more
Preface Tumor development and progression occur as a result of cumulative acquisition of genetic alterations affecting oncogenes and tumor suppressor genes. As a consequence of these alterations the arising tumor gains some fatal properties such as increased cell proliferation and decreased apoptosis, resulting in a net accumulation of tra- formed cells. Once a critical volume is achieved, lack of oxygen and nutrients limits further growth. To overcome this obstacle, the tumor cells initiate a program focused on the formation of new blood vessels within the host tissue. This process is termed tumor angiogenesis and contributes to the progression of most ... Read more
Product Details
Format
Hardback
Publication date
2007
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
845
Condition
New
Number of Pages
845
Place of Publication
Berlin, Germany
ISBN
9783540331766
SKU
V9783540331766
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Tumor Angiogenesis
From the reviews: "The chapters in Tumor Angiogenesis are divided into four sections … . Tumor Angiogenesis is an outstanding overview of the basic science and translational aspects of angiogenesis. … To fully capitalize on antiangiogenic therapy, we must continue to have an open dialogue between basic scientists and clinical investigators. This book will serve ... Read more