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Vesicle Trafficking in Cancer
Yarden Yosef
€ 182.40
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Description for Vesicle Trafficking in Cancer
Hardcover. This book reports on recent progress in understanding the role of vesicular transport in cancer, including recent studies which raise the intriguing possibility that drug-mediated normalization of vesicular transport may serve as a therapeutic goal in cancer. Editor(s): Yarden, Yosef; Tarcic, Gabi. Num Pages: 393 pages, biography. BIC Classification: MJCL; PSF. Category: (P) Professional & Vocational. Dimension: 242 x 161 x 28. Weight in Grams: 732.
Endocytosis and vesicular trafficking determine the landscape of the cell’s exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers. Hence, endocytosis is involved in signal transduction, cell adhesion and migration, as well as metabolism. To exploit these fundamental processes, malignancies subtly and multiply manipulate the endocytosis and the subsequent trafficking of protein cargoes. This is achieved by simultaneously altering the cytoskeleton, vesicle budding, cargo sorting and intracellular degradation. By highlighting the underlying molecular processes and concentrating on specific examples, this book reviews ... Read more
Endocytosis and vesicular trafficking determine the landscape of the cell’s exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers. Hence, endocytosis is involved in signal transduction, cell adhesion and migration, as well as metabolism. To exploit these fundamental processes, malignancies subtly and multiply manipulate the endocytosis and the subsequent trafficking of protein cargoes. This is achieved by simultaneously altering the cytoskeleton, vesicle budding, cargo sorting and intracellular degradation. By highlighting the underlying molecular processes and concentrating on specific examples, this book reviews ... Read more
Product Details
Format
Hardback
Publication date
2013
Publisher
Springer-Verlag New York Inc. United States
Number of pages
350
Condition
New
Number of Pages
393
Place of Publication
New York, NY, United States
ISBN
9781461465270
SKU
V9781461465270
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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