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Progress in Drug Research
Ernst Jucker
€ 67.81
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Description for Progress in Drug Research
Paperback. Series: Progress in Drug Research. Num Pages: 334 pages, biography. BIC Classification: MMG; MQP. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 18. Weight in Grams: 577.
Due tothedevelopmentofdrugresistanceandotherlimitationsinthe treat- ment of AIDS patients with reverse transcriptase (RT) inhibitors like zidovu- dineandothers, itbecamenecessarytoexploreantiviralagentsactingontar- getsotherthan RT. Inthepastfewyears, hundredsofHIVproteaseinhibitoLs have been synthesized and tested. Among these protease inhibitors, saquinavir, ritonavir, indinavir and nelfinavir have been marketed during 1995-1997. In this review, emphasis is placed on the development of HIV protease inhibitors as antiviral agents against HIV, structure-activity rela- tionship (SAR) analysis ofsaquinavirand relatedcompounds, comparisonof four marketed HIV protease inhibitors, and future prospect in developing new anti-HIV drugs. 2 Introduction HIV protease inhibitors 3 HIV protease as a target for chemotherapy HIV protease was first suggested as a potential target ... Read more
Due tothedevelopmentofdrugresistanceandotherlimitationsinthe treat- ment of AIDS patients with reverse transcriptase (RT) inhibitors like zidovu- dineandothers, itbecamenecessarytoexploreantiviralagentsactingontar- getsotherthan RT. Inthepastfewyears, hundredsofHIVproteaseinhibitoLs have been synthesized and tested. Among these protease inhibitors, saquinavir, ritonavir, indinavir and nelfinavir have been marketed during 1995-1997. In this review, emphasis is placed on the development of HIV protease inhibitors as antiviral agents against HIV, structure-activity rela- tionship (SAR) analysis ofsaquinavirand relatedcompounds, comparisonof four marketed HIV protease inhibitors, and future prospect in developing new anti-HIV drugs. 2 Introduction HIV protease inhibitors 3 HIV protease as a target for chemotherapy HIV protease was first suggested as a potential target ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer Basel Switzerland
Number of pages
334
Condition
New
Series
Progress in Drug Research
Number of Pages
326
Place of Publication
Basel, Switzerland
ISBN
9783034897983
SKU
V9783034897983
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Progress in Drug Research