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Recombinant DNA Technologies in Neuroendocrinology
Hiroo . Ed(S): Imura
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Description for Recombinant DNA Technologies in Neuroendocrinology
Paperback. Editor(s): Imura, Hiroo. Series: Current Topics in Neuroendocrinology. Num Pages: 222 pages, 16 black & white illustrations, 6 black & white tables, biography. BIC Classification: MJG; MQW; PSAN. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 12. Weight in Grams: 358.
1.1 Mechanism of Action of Glucocorticoid Hormones The current model of glucocorticoid hormone action is summarized in Fig. 1. After synthesis, glucocorticoids are secreted into the blood stream and trans- ported to target cells where they bind with high affinity (K-1O-9M) and d specificity to the intracellular glucocorticoid receptor (GR) protein. The sub- cellular localization of hormone-free GR is still a controversial issue. However, most data support the idea that unliganded GR is in the cytoplasmic compartment or loosely associated with the nucleus (Picard and Yamamoto 1987; Gustafsson et al. 1987 and references therein; LaFond et al. 1988; Gasc et ... Read more
1.1 Mechanism of Action of Glucocorticoid Hormones The current model of glucocorticoid hormone action is summarized in Fig. 1. After synthesis, glucocorticoids are secreted into the blood stream and trans- ported to target cells where they bind with high affinity (K-1O-9M) and d specificity to the intracellular glucocorticoid receptor (GR) protein. The sub- cellular localization of hormone-free GR is still a controversial issue. However, most data support the idea that unliganded GR is in the cytoplasmic compartment or loosely associated with the nucleus (Picard and Yamamoto 1987; Gustafsson et al. 1987 and references therein; LaFond et al. 1988; Gasc et ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
222
Condition
New
Series
Current Topics in Neuroendocrinology
Number of Pages
222
Place of Publication
Berlin, Germany
ISBN
9783642775055
SKU
V9783642775055
Shipping Time
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Ref
99-15
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