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Cytotoxic Drug Resistance Mechanisms
Brown, Robert; Boger-Brown, Uta
€ 126.90
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Description for Cytotoxic Drug Resistance Mechanisms
Hardback. Describes methods for examining the mechanisms of cellular resistance to anticancer cytotoxics in human tumors. This work illuminates clinically relevant mechanisms used as markers of the biological response to anticancer biotherapeutics. It also includes troubleshooting tips that allow you to study a variety of drug resistance mechanisms. Series: Methods in Molecular Medicine. Num Pages: 238 pages, biography. BIC Classification: MJCL2; MMG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 19. Weight in Grams: 1210.
There is now a range of cytotoxic drugs that have considerable clinical usefulness in producing responses in tumors and even, in a small proportion of cases, cure. However, the acquisition of drug resistance is a major clinical problem and is perhaps the main limiting factor in successful treatment of cancer. Thus, a tumor initially sensitive to chemotherapy will, in the majority of cases, eventually recur as a resistant tumor, which will then progress. Much of our understanding of drug resistance mechanisms comes from the study of tumor cell lines grown in tissue culture. We now understand many of the - ... Read more
There is now a range of cytotoxic drugs that have considerable clinical usefulness in producing responses in tumors and even, in a small proportion of cases, cure. However, the acquisition of drug resistance is a major clinical problem and is perhaps the main limiting factor in successful treatment of cancer. Thus, a tumor initially sensitive to chemotherapy will, in the majority of cases, eventually recur as a resistant tumor, which will then progress. Much of our understanding of drug resistance mechanisms comes from the study of tumor cell lines grown in tissue culture. We now understand many of the - ... Read more
Product Details
Format
Hardback
Publication date
1999
Publisher
Humana Press Inc. United States
Number of pages
238
Condition
New
Series
Methods in Molecular Medicine
Number of Pages
238
Place of Publication
Totowa, NJ, United States
ISBN
9780896036031
SKU
V9780896036031
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Cytotoxic Drug Resistance Mechanisms
"This timely book will greatly benefit a wide array of individuals interested in cancer therapeutics, at both the clinical and basic science level. The editors and contributors did a good job of concisely presenting otherwise disparate methodologies in the context of a broad research field with the uniting purpose of understanding the biology underlying resistance to cancer chemotherapy. "-Doody's Health ... Read more