Drug-DNA Interaction Protocols
K. R. . Ed(S): Fox
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Description for Drug-DNA Interaction Protocols
Hardback. The last few years have witnessed the creation of new generations of sequence reading compounds, which have incredible potential for targeting specific DNA sequences. In this authoritative and current book, expert researchers explore these compounds. Editor(s): Fox, K. R. Series: Methods in Molecular Biology. Num Pages: 311 pages, 102 black & white illustrations, 1 colour illustrations, 11 black & white tables, biograp. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 25. Weight in Grams: 894.
DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has ... Read more
DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity. On the basis of this information, new generations of sequence reading compounds (including triplex forming oligonucleotides and minor groove binding ligands) have been prepared, which have the potential for targeting specifc DNA sequences as anti-gene agents. Within the last 10 years, it has ... Read more
Product Details
Format
Hardback
Publication date
2009
Publisher
Humana Press Inc. United States
Number of pages
311
Condition
New
Series
Methods in Molecular Biology
Number of Pages
311
Place of Publication
Totowa, NJ, United States
ISBN
9781603274173
SKU
V9781603274173
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Drug-DNA Interaction Protocols
From the reviews of the second edition: “Provides authoritative and current information on the binding of new generations of DNA sequence reading compounds … . The intended audience includes postgraduates, postdoctoral workers, and established scientists … . even clinical investigators such as oncologists may find this book quite useful. … This well-illustrated book of chapters written by leading experts ... Read more