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G-Protein-Coupled Receptors in Drug Discovery
Wayne R. . Ed(S): Leifert
€ 130.15
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Description for G-Protein-Coupled Receptors in Drug Discovery
Hardback. In this authoritative volume, experts in the field provide a range of classic and cutting-edge laboratory protocols developed for GPCR research. This volume serves to aid all those who wish to further the vital research in their GPCR drug discovery programs. Editor(s): Leifert, Wayne R. Series: Methods in Molecular Biology. Num Pages: 376 pages, 18 black & white tables, biography. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 260 x 193 x 23. Weight in Grams: 930.
The G protein-coupled receptors (GPCRs) and associated peripheral G proteins underpin a multitude of physiological processes. The GPCRs represent one of the largest superfamilies in the human genome and are a significant target for bioactive and drug discovery programs. It is estimated that greater than 50% of all drugs, including those in development, currently target GPCRs. Many of the characterized GPCRs have known ligands; however, approximately 20% of GPCRs are described as orphan GPCRs, apparent GPCRs that share the generic high-level structure charact- istic of GPCRs but whose endogenous ligand is not known. Therefore, it is expected that the field ... Read more
The G protein-coupled receptors (GPCRs) and associated peripheral G proteins underpin a multitude of physiological processes. The GPCRs represent one of the largest superfamilies in the human genome and are a significant target for bioactive and drug discovery programs. It is estimated that greater than 50% of all drugs, including those in development, currently target GPCRs. Many of the characterized GPCRs have known ligands; however, approximately 20% of GPCRs are described as orphan GPCRs, apparent GPCRs that share the generic high-level structure charact- istic of GPCRs but whose endogenous ligand is not known. Therefore, it is expected that the field ... Read more
Product Details
Format
Hardback
Publication date
2009
Publisher
Humana Press Inc. United States
Number of pages
376
Condition
New
Series
Methods in Molecular Biology
Number of Pages
376
Place of Publication
Totowa, NJ, United States
ISBN
9781603273169
SKU
V9781603273169
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-3
Reviews for G-Protein-Coupled Receptors in Drug Discovery
From the reviews: “To fully understand the GPCR drug discovery process one should … have wide knowledge of the methods/protocols used in this process. This book serves this exact purpose. … It’s biggest strength is a clear description of every aspect of GPCR drug discovery process, which is easy to understand even for a non-expert in the respective field. ... Read more