Stock image for illustration purposes only - book cover, edition or condition may vary.
Human Immunodeficiency Virus Reverse Transcriptase
. Ed(S): Legrice, Stuart F. J; Gotte, Matthias
€ 132.47
FREE Delivery in Ireland
Description for Human Immunodeficiency Virus Reverse Transcriptase
Paperback. This book covers coordination of RT-associated DNA polymerase and ribonuclease H activities, mechanisms of action and perspectives on NRTIs and NNRTIs, strategies for targeting the RT enzyme and mechanisms in HIV variability and development of drug resistance. Editor(s): LeGrice, Stuart F. J; Gotte, Matthias. Num Pages: 371 pages, biography. BIC Classification: MJCJ; MJCM; MMFM. Category: (G) General (US: Trade). Dimension: 235 x 155 x 20. Weight in Grams: 569.
The Reverse Transcriptase (RT) of Human Immunodeficiency Virus Type 1 (HIV-1) arguably ranks amongst one of the most extensively studied retroviral enzymes. Heterologous expression and purification of HIV-1 RT in the early eighties, approval of the first nucleoside analogue RT inhibitor (NRTI) in 1987, discovery of resistance to RT inhibitors, approval of the first non-nucleoside analogue RT inhibitor (NNRTI) in 1996 and the various crystal structures of RT with and without bound substrate(s) and/or inhibitors represent only a few of the important milestones that describe the a bench-to-bedside success in the continuing effort to combat HIV-1 infection and its consequences. ... Read more
The Reverse Transcriptase (RT) of Human Immunodeficiency Virus Type 1 (HIV-1) arguably ranks amongst one of the most extensively studied retroviral enzymes. Heterologous expression and purification of HIV-1 RT in the early eighties, approval of the first nucleoside analogue RT inhibitor (NRTI) in 1987, discovery of resistance to RT inhibitors, approval of the first non-nucleoside analogue RT inhibitor (NNRTI) in 1996 and the various crystal structures of RT with and without bound substrate(s) and/or inhibitors represent only a few of the important milestones that describe the a bench-to-bedside success in the continuing effort to combat HIV-1 infection and its consequences. ... Read more
Product Details
Format
Paperback
Publication date
2015
Publisher
Springer-Verlag New York Inc. United States
Number of pages
371
Condition
New
Number of Pages
361
Place of Publication
New York, United States
ISBN
9781489999535
SKU
V9781489999535
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Human Immunodeficiency Virus Reverse Transcriptase