Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models
Joel S. Owen
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Description for Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models
Hardcover. Providing a user-friendly, hands-on introduction to the most powerful tool for population PK/PD models, Introduction to Population PK/PD Analysis with Nonlinear Mixed Effects Models introduces the reader to the NONMEM system, a powerful tool for pharmacokinetic / pharmacodynamic analysis. Num Pages: 320 pages, illustrations. BIC Classification: MMG; PBWH. Category: (P) Professional & Vocational. Dimension: 242 x 155 x 21. Weight in Grams: 574.
This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.
• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects
• Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment
• Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control
... Read more
This book provides a user-friendly, hands-on introduction to the Nonlinear Mixed Effects Modeling (NONMEM) system, the most powerful tool for pharmacokinetic / pharmacodynamic analysis.
• Introduces requisite background to using Nonlinear Mixed Effects Modeling (NONMEM), covering data requirements, model building and evaluation, and quality control aspects
• Provides examples of nonlinear modeling concepts and estimation basics with discussion on the model building process and applications of empirical Bayesian estimates in the drug development environment
• Includes detailed chapters on data set structure, developing control streams for modeling and simulation, model applications, interpretation of NONMEM output and results, and quality control
... Read more
Product Details
Publisher
John Wiley & Sons Inc
Format
Hardback
Publication date
2014
Condition
New
Weight
574g
Number of Pages
320
Place of Publication
New York, United States
ISBN
9780470582299
SKU
V9780470582299
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-50
About Joel S. Owen
Joel S. Owen is Professor of Pharmaceutics at Union University, Jackson, Tennessee and President and Principal Scientist of Joel S. Owen, LLC. He has led workshops on NONMEM and PK/PD modeling concepts and applications and served as Director PK/PD at Cognigen Corporation in Buffalo, New York. He has published 16 articles in research publications. Jill Fiedler-Kelly is Vice ... Read more
Reviews for Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models
“This book may make the “User Guide V experience” a story from the good old times for the next generation of pharmacometricians.” (CPT: Pharmacometrics & Systems Pharmacology, 22 December 2014)