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Rongshi Li - Kinase Inhibitor Drugs - 9780470278291 - V9780470278291
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Kinase Inhibitor Drugs

€ 180.45
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Description for Kinase Inhibitor Drugs Hardcover. Kinase Inhibitor Drugs covers a wide and comprehensive range of topics about kinase-targeted inhibitors in cancer therapy, one of the hottest drug targets in modern drug discovery. Series: Wiley Series in Drug Discovery and Development. Num Pages: 510 pages, Illustrations, (some col.). BIC Classification: MJCL2; MMG. Category: (P) Professional & Vocational. Dimension: 244 x 162 x 29. Weight in Grams: 882.
A comprehensive resource on case studies of marketed kinase drugs and promising drug trials

Since the discovery of protein kinase activity in 1954, the field of protein kinase drug discovery has advanced dramatically. With the ongoing clinical success of the Bcr-Abl kinase inhibitor Gleevec in the treatment of chronic myelogenous leukemia and seven additional marketed kinase inhibitor drugs, researchers have compelling evidence that kinase inhibitors can be highly efficacious in the treatment of diseases caused by aberrant activity of protein kinase. Currently more than 100 protein kinase inhibitors are in clinical development.

In one comprehensive volume, the editors, Dr. ... Read more

  • Case studies from leading investigators and experts in the field that provide firsthand accounts of kinase inhibitor discovery

  • Current thinking on kinase structure, biochemistry, and signal transduction pathways

  • Information on state-of-the-art technologies and tools such as structure-based and fragment-based drug discovery

  • A lineup of clinical-phase growth factor receptor inhibitors

  • Inhibitors of cell cycle kinases

  • The discovery of allosteric inhibitors of MEK kinase

  • Information on pharmacogenomics and its application to kinase inhibitor clinical development

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Product Details

Format
Hardback
Publication date
2009
Publisher
John Wiley and Sons Ltd United Kingdom
Number of pages
510
Condition
New
Series
Wiley Series in Drug Discovery and Development
Number of Pages
528
Place of Publication
New York, United States
ISBN
9780470278291
SKU
V9780470278291
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-50

About Rongshi Li
Rongshi Li, PhD, is an Associate Professor in the Drug Discovery Department at H. Lee Moffitt Cancer Center and Research Institute in Tampa, Florida. Jeffrey A. Stafford, PhD, has led drug discovery research at GlaxoSmithKline, Syrrx, and Takeda. He is a co-inventor of the tyrosine kinase inhibitor, pazopanib (Armala).

Reviews for Kinase Inhibitor Drugs
"In conclusion, I strongly recommend this book to anyone who is interested and new to the field of kinase inhibitors. Indeed, I believe this book should not merely sit on the shelves of kinase experts, but should be used frequently for reference." (ChemMedChem, 2010) "Delivers what the title promises: a comprehensive treatment of drugs that inhibit ... Read more

Goodreads reviews for Kinase Inhibitor Drugs


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