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Resistance of Cancer Cells to Ctl-Mediated Immunotherapy
. Ed(S): Chouaib, Salem; Bonavida, Benjamin
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Description for Resistance of Cancer Cells to Ctl-Mediated Immunotherapy
Hardback. Editor(s): Chouaib, Salem; Bonavida, Benjamin. Series: Resistance to Targeted Anti-Cancer Therapeutics. Num Pages: 372 pages, 11 black & white illustrations, 27 colour illustrations, 4 black & white tables, biograph. BIC Classification: MBGR; MJCL; MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 21. Weight in Grams: 819.
This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, ... Read more
This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, ... Read more
Product Details
Format
Hardback
Publication date
2015
Publisher
Springer International Publishing AG Switzerland
Number of pages
372
Condition
New
Series
Resistance to Targeted Anti-Cancer Therapeutics
Number of Pages
353
Place of Publication
Cham, Switzerland
ISBN
9783319178066
SKU
V9783319178066
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About . Ed(S): Chouaib, Salem; Bonavida, Benjamin
Benjamin Bonavida, Ph.D., is Professor, UCLA David Geffen School of Medicine for the Department of Microbiology, Immunology & Molecular Genetics. He is also Member, Department of Defense Congressionally Directed Medical Research Program, Member, National Cancer Institute SPORE Program, Member, International Scientific Advisory Board of the Israel Cancer Research Foundation, among other accomplishments. He is currently a scientific reviewer for several ... Read more
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