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Role of Capsaicin in Oxidative Stress and Cancer
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Description for Role of Capsaicin in Oxidative Stress and Cancer
Hardcover. This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress and much more. Editor(s): Srivastava, Sanjay K. Series: Diet and Cancer. Num Pages: 187 pages, 3 black & white tables, biography. BIC Classification: MJCL; MMF; MMG. Category: (P) Professional & Vocational. Dimension: 244 x 162 x 17. Weight in Grams: 460.
This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress; involvement of mitochondrial respiratory chain in the production of ROS; prevention of chemically-induced carcinogenesis, discussion on TRPV-1 receptor mediated or independent anti-cancer effects; identification of p53 activation as a possible mechanism; involvement of Cox-2 in apoptosis, suppression of transcription factors such as NF-kB and STAT-3; inhibition of cell survival pathways including PI3K/Akt and the involvement of intrinsic mitochondrial cell death pathway.
Product Details
Format
Hardback
Publication date
2013
Publisher
Springer Netherlands
Number of pages
187
Condition
New
Series
Diet and Cancer
Number of Pages
178
Place of Publication
Dordrecht, Netherlands
ISBN
9789400763166
SKU
V9789400763166
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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