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The Design of Synthetic Inhibitors of Thrombin (Advances in Experimental Medicine and Biology)
Claeson, G. Ed., International Symposium On The Design Of
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Description for The Design of Synthetic Inhibitors of Thrombin (Advances in Experimental Medicine and Biology)
Hardcover. Editor(s): Claeson, Goran. Series: Advances in Experimental Medicine and Biology. Num Pages: 256 pages, biography. BIC Classification: MFG; MMG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 19. Weight in Grams: 1570.
In one generation, the numerous factors involved in blood coagulation have become real protein entities, isolated in pure form, expressed by recombinant DNA techniques, and subjected to structure elucidation by the modem methods of physical chemistry, viz. , X-ray diffraction, and NMR, ESR and fluorescence spectroscopy. The major milestone in this field was the breakthrough achieved by W. Bode, R. Huber and their colleagues in 1989 in of human a-thrombin, inhibited with D-Phe-Pro-Arg determining the crystal structure chioromethyl ketone. The availability of this structure will greatly facilitate the interpretation of experiments designed to gain an understanding of the interatomic interactions ... Read more
In one generation, the numerous factors involved in blood coagulation have become real protein entities, isolated in pure form, expressed by recombinant DNA techniques, and subjected to structure elucidation by the modem methods of physical chemistry, viz. , X-ray diffraction, and NMR, ESR and fluorescence spectroscopy. The major milestone in this field was the breakthrough achieved by W. Bode, R. Huber and their colleagues in 1989 in of human a-thrombin, inhibited with D-Phe-Pro-Arg determining the crystal structure chioromethyl ketone. The availability of this structure will greatly facilitate the interpretation of experiments designed to gain an understanding of the interatomic interactions ... Read more
Product Details
Format
Hardback
Publication date
1994
Publisher
Springer
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
246
Place of Publication
, United States
ISBN
9780306445934
SKU
V9780306445934
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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