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The Future of Predictive Safety Evaluation. In Two Volumes Volumes 2.
. Ed(S): Worden, A. N.; Parke, D. V.; Marks, J.
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Description for The Future of Predictive Safety Evaluation. In Two Volumes Volumes 2.
Paperback. Editor(s): Worden, A. N.; Parke, D. V.; Marks, J. Num Pages: 324 pages, biography. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 17. Weight in Grams: 498.
Reproduction and fetal development in humans and experimental animals may be adversely affected by a wide range of drugs and environmental agents. They may be toxic in the parental generation leading to impaired germ cell formation, loss of reproductive poten tial and infertility following chronic exposure. Deviant fetal development occurs as a consequence of cellular damage at sensi tive stages in development. Changes seen range from intrauterine mortality and structural malformation to growth retardation with physiological and behavioural defects. Concepts on the mechanism of action of teratogens are discussed with reference to some better-known agents. Presently, regulatory authorities prefer whole ... Read more
Reproduction and fetal development in humans and experimental animals may be adversely affected by a wide range of drugs and environmental agents. They may be toxic in the parental generation leading to impaired germ cell formation, loss of reproductive poten tial and infertility following chronic exposure. Deviant fetal development occurs as a consequence of cellular damage at sensi tive stages in development. Changes seen range from intrauterine mortality and structural malformation to growth retardation with physiological and behavioural defects. Concepts on the mechanism of action of teratogens are discussed with reference to some better-known agents. Presently, regulatory authorities prefer whole ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer Netherlands
Number of pages
324
Condition
New
Number of Pages
320
Place of Publication
Dordrecht, Netherlands
ISBN
9789401079365
SKU
V9789401079365
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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