Combinatorial Library Methods and Protocols
Lisa B . Ed(S): English
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Description for Combinatorial Library Methods and Protocols
Hardback. Presents a series of computational and laboratory methods for the design, synthesis, quality control, screening, and purification of just such combinatorial libraries. This book provides techniques for the preparation of encoded combinatorial libraries, for the synthesis of DNA-binding polyamides, and for combinatorial receptors. Editor(s): English, Lisa B. Series: Methods in Molecular Biology. Num Pages: 383 pages, biography. BIC Classification: GLC; MQP. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 25. Weight in Grams: 1670.
The continued successes of large- and small-scale genome sequencing projects are increasing the number of genomic targets available for drug d- covery at an exponential rate. In addition, a better understanding of molecular mechanisms—such as apoptosis, signal transduction, telomere control of ch- mosomes, cytoskeletal development, modulation of stress-related proteins, and cell surface display of antigens by the major histocompatibility complex m- ecules—has improved the probability of identifying the most promising genomic targets to counteract disease. As a result, developing and optimizing lead candidates for these targets and rapidly moving them into clinical trials is now a critical juncture in pharmaceutical ... Read more
The continued successes of large- and small-scale genome sequencing projects are increasing the number of genomic targets available for drug d- covery at an exponential rate. In addition, a better understanding of molecular mechanisms—such as apoptosis, signal transduction, telomere control of ch- mosomes, cytoskeletal development, modulation of stress-related proteins, and cell surface display of antigens by the major histocompatibility complex m- ecules—has improved the probability of identifying the most promising genomic targets to counteract disease. As a result, developing and optimizing lead candidates for these targets and rapidly moving them into clinical trials is now a critical juncture in pharmaceutical ... Read more
Product Details
Format
Hardback
Publication date
2002
Publisher
Humana Press Inc. United States
Number of pages
383
Condition
New
Series
Methods in Molecular Biology
Number of Pages
383
Place of Publication
Totowa, NJ, United States
ISBN
9780896039803
SKU
V9780896039803
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Combinatorial Library Methods and Protocols
"...an excellent work that covers many important aspects, gives easy access to literature for further study, and contains much practical advice. As it describes many different tools and techniques it is especially suitable for beginners in combinatorial chemistry, and deserves to be added to the list of well presented works in this field." - Angewandte Chemie "The ... Read more