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Oligonucleotide Synthesis
Piet . Ed(S): Herdewijn
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Description for Oligonucleotide Synthesis
Paperback. Editor(s): Herdewijn, Piet. Series: Methods in Molecular Biology. Num Pages: 436 pages, 142 black & white illustrations, biography. BIC Classification: MQP. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 25. Weight in Grams: 660.
A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an ... Read more
A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using molecular beacons to monitor the PCR amplification process, nuclease footprinting to study the sequence-selective binding of small molecules of DNA, nucleic acid libraries, and the use of small interference RNA (siRNA) as an ... Read more
Product Details
Format
Paperback
Publication date
2010
Publisher
Humana Press Inc. United States
Number of pages
436
Condition
New
Series
Methods in Molecular Biology
Number of Pages
436
Place of Publication
Totowa, NJ, United States
ISBN
9781617374418
SKU
V9781617374418
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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