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. Ed(S): Yona, Simon; Stacey, Martin - Adhesion-GPCRs - 9781441979124 - V9781441979124
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Adhesion-GPCRs

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Description for Adhesion-GPCRs Hardback. This book examines key concepts and recent advances in adhesion-GPCR biology. It also describes the expression of adhesion-GPCRs within the male reproductive tract and reviews their potential contribution in reproductive competence. Editor(s): Yona, Simon; Stacey, Martin. Series: Advances in Experimental Medicine and Biology. Num Pages: 199 pages, 10 black & white tables, biography. BIC Classification: MBGR; MFGC; PSBC. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 14. Weight in Grams: 609.
Upon completion of the human genome project over 800 G protein-coupled receptor 1 (GPCR) genes, subdivided into five categories, were identified. These receptors sense a diverse array of stimuli, including peptides, ions, lipid analogues, light and odour, in a discriminating fashion. Subsequently, they transduce a signal from the ligand–receptor complex into numerous cellular responses. The importance of GPCRs is further reflected in the fact that they constitute the most common target for therapeutic drugs across a 2 wide range of human disorders. Phylogenetic analysis of GPCRs produced the GRAFS classification system, which subdivides GPCRs into five discrete families: glutamate, rhodopsin, ... Read more

Product Details

Format
Hardback
Publication date
2011
Publisher
Springer-Verlag New York Inc. United States
Number of pages
199
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
199
Place of Publication
New York, NY, United States
ISBN
9781441979124
SKU
V9781441979124
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

About . Ed(S): Yona, Simon; Stacey, Martin
Simon Yona, PhD, graduated from Kings College, University London with a BSc in Physiology and a MSc in Pharmacology, before completing a PhD with Prof. R.J. Flower FRS and Prof. M. Perretti, at St. Bartholomew’s Hospital, University of London. Following his doctorate Simon took up a Postdoctoral Research position with Prof. S. Gordon FRS, at the Sir William Dunn School ... Read more

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