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DNA Alterations in Lynch Syndrome
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Description for DNA Alterations in Lynch Syndrome
Hardcover. This book surveys the genetic and epigenetic basis of Lynch syndrome, evaluating its clinical features and analyzing molecular tools for identifying mutations responsible for the syndrome; includes functional assays for assessing identified mutations. Editor(s): Vogelsang, Matjaz. Num Pages: 195 pages, 8 black & white tables, biography. BIC Classification: MBGR; MFN; MJCL; MJH. Category: (P) Professional & Vocational. Dimension: 244 x 160 x 14. Weight in Grams: 440.
Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. An estimated 37,000 of diagnosed colorectal cancer cases worldwide are attributed to Lynch syndrome each year. Intensive cancer screening, with early initiation and frequent follow-up, can reduce colorectal cancer incidence and mortality in LS patients. This book provides an up-to-date overview on the genetic and epigenetic basis of Lynch syndrome. It evaluates clinical features of the disease and critically comments on molecular tools available for identifying mutations responsible for Lynch syndrome; in addition the importance of functional assays that can help ... Read more
Lynch syndrome (LS) is the most common cause of inherited colorectal cancer, a disease with a high mortality rate. An estimated 37,000 of diagnosed colorectal cancer cases worldwide are attributed to Lynch syndrome each year. Intensive cancer screening, with early initiation and frequent follow-up, can reduce colorectal cancer incidence and mortality in LS patients. This book provides an up-to-date overview on the genetic and epigenetic basis of Lynch syndrome. It evaluates clinical features of the disease and critically comments on molecular tools available for identifying mutations responsible for Lynch syndrome; in addition the importance of functional assays that can help ... Read more
Product Details
Format
Hardback
Publication date
2013
Publisher
Springer Netherlands
Number of pages
150
Condition
New
Number of Pages
195
Place of Publication
Dordrecht, Netherlands
ISBN
9789400765962
SKU
V9789400765962
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for DNA Alterations in Lynch Syndrome
From the reviews: “This highly specialized book is an extensive, multiauthored discussion of Lynch syndrome. … From health professionals implementing general health surveillance to oncologists and geneticists dealing with populations at risk of Lynch syndrome, this is a must-have book. Cancer genetics clinics should count this as part of their resources to provide accurate information to their patients. … ... Read more