Gadd45 Stress Sensor Genes
. Ed(S): Liebermann, Dan A.; Hoffman, Barbara
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Description for Gadd45 Stress Sensor Genes
paperback. This book presents a comprehensive picture of the unique global role Gadd45 genes play as stress sensors and the molecular pathways involved. Editor(s): Liebermann, Dan A.; Hoffman, Barbara. Series: Advances in Experimental Medicine and Biology. Num Pages: 144 pages, 7 black & white illustrations, 11 colour illustrations, biography. BIC Classification: MFN; PSB. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 8. Weight in Grams: 232.
Emerging evidence indicates that the Gadd45 family of genes play a unique and critical role as sensors of stress, including genotoxic, physiological and oncogenic stress. The stress response Gadd45 family of genes (Gadd45a, Gadd45b & Gadd45g), discovered by Dr. Liebermann and other researchers, encode for small (18 kd) nuclear/cytoplasmic proteins). These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. In spite of marked similarities, Gadd45 genes are regulated differently & exhibit functional diversity. Gadd45 are implicated in cell cycle arrest, DNA demethylation & repair, apoptosis, cell survival, genomic stability, inflammation, & in response ... Read more
Emerging evidence indicates that the Gadd45 family of genes play a unique and critical role as sensors of stress, including genotoxic, physiological and oncogenic stress. The stress response Gadd45 family of genes (Gadd45a, Gadd45b & Gadd45g), discovered by Dr. Liebermann and other researchers, encode for small (18 kd) nuclear/cytoplasmic proteins). These genes are rapidly induced by a wide variety of endogenous and exogenous stress stimuli. In spite of marked similarities, Gadd45 genes are regulated differently & exhibit functional diversity. Gadd45 are implicated in cell cycle arrest, DNA demethylation & repair, apoptosis, cell survival, genomic stability, inflammation, & in response ... Read more
Product Details
Format
Paperback
Publication date
2016
Publisher
Springer United States
Number of pages
144
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
134
Place of Publication
New York, United States
ISBN
9781493953905
SKU
V9781493953905
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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