Gene Targeting Protocols (Methods in Molecular Biology)
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Description for Gene Targeting Protocols (Methods in Molecular Biology)
Paperback. Editor(s): Kmiec, Eric B. Series: Methods in Molecular Biology. Num Pages: 248 pages, biography. BIC Classification: MFN. Category: (P) Professional & Vocational. Dimension: 230 x 153 x 19. Weight in Grams: 386.
The potential now exists in many experimental systems to transfer a cloned, modified gene back into the genome of the host organism. In the ideal situation, the cloned gene is returned to its homologous location in the genome and becomes inserted at the target locus. This process is a controlled means for the repair of DNA damage and ensures accurate chromosome disjunction during meiosis. The paradigm for thinking about the mechanism of this p- cess has emerged primarily from two sources: (1) The principles of reaction mechanics have come from detailed biochemical analyses of the RecA protein purified from Escherichia ... Read more
The potential now exists in many experimental systems to transfer a cloned, modified gene back into the genome of the host organism. In the ideal situation, the cloned gene is returned to its homologous location in the genome and becomes inserted at the target locus. This process is a controlled means for the repair of DNA damage and ensures accurate chromosome disjunction during meiosis. The paradigm for thinking about the mechanism of this p- cess has emerged primarily from two sources: (1) The principles of reaction mechanics have come from detailed biochemical analyses of the RecA protein purified from Escherichia ... Read more
Product Details
Format
Paperback
Publication date
2013
Publisher
Humana Press
Condition
New
Series
Methods in Molecular Biology
Number of Pages
233
Place of Publication
Totowa, NJ, United States
ISBN
9781489941589
SKU
V9781489941589
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Gene Targeting Protocols (Methods in Molecular Biology)
"The book also has several techniques for using oligonucleotides in gene targeting, a methodology that may well revolutionize the entire field." - Cellular and Molecular Biology