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Lead-Seeking Approaches
Matthew M. . Ed(S): Hayward
€ 194.82
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Description for Lead-Seeking Approaches
Hardback. Contains topics that include, Overview of Hit to Lead: The Medicinal Chemist's Role from HTS Retest to Lead Optimization Hand Off; High Throughput Screening in the 21st Century; Lead Discovery Using Virtual Screening; and NMR Spectroscopy in Fragment Based Drug Design. Editor(s): Hayward, Matthew M. Series: Topics in Medicinal Chemistry. Num Pages: 217 pages, 26 black & white illustrations, 10 colour illustrations, 8 black & white tables, biograph. BIC Classification: MF; PNN; PSAN. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 18. Weight in Grams: 556.
High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits ... Read more
High quality leads provide the foundation for the discovery of successful clinical development candidates, and therefore the identi?cation of leads is an essential part of drug discovery. The process for the identi?cation of leads generally starts with the screening of a compound collection, either an HTS of a relatively large compound collection (hundreds of thousands to one million plus compounds) or a more focused screen of a smaller set of compounds that have been preselected for the target of interest. Virtual screening methods such as structure-based or pharmacophore-based searches can complement or replace one of the above approaches. Once hits ... Read more
Product Details
Format
Hardback
Publication date
2009
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
217
Condition
New
Series
Topics in Medicinal Chemistry
Number of Pages
217
Place of Publication
Berlin, Germany
ISBN
9783642010743
SKU
V9783642010743
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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