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Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development
. Ed(S): Bonifer, Constanze; Cockerill, Peter
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Description for Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development
hardcover. Transcriptional and Epigenetic Mechanisms Regulating Normal and Aberrant Blood Cell Development Editor(s): Bonifer, Constanze; Cockerill, Peter. Series: Epigenetics and Human Health. Num Pages: 429 pages, 49 colour illustrations, biography. BIC Classification: MFN; MJCL. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 33. Weight in Grams: 806.
During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and megakaryocytes. To tightly control the enormous proliferative potential of developing blood cells, an intricately balanced signaling and transcription network has evolved that ensures that the different cell types are formed at the right time and in the right numbers. Intricate regulatory mechanisms ensure that blood cells function properly and have a determined life span. Moreover, in the adaptive immune system, long-lived memory cells have evolved that ensure that when pathogens have been seen once they will never ... Read more
During vertebrate hematopoiesis many specialized cell types are formed with vastly different functions such as B cells, T cells, granulocytes, macrophages, erythrocytes and megakaryocytes. To tightly control the enormous proliferative potential of developing blood cells, an intricately balanced signaling and transcription network has evolved that ensures that the different cell types are formed at the right time and in the right numbers. Intricate regulatory mechanisms ensure that blood cells function properly and have a determined life span. Moreover, in the adaptive immune system, long-lived memory cells have evolved that ensure that when pathogens have been seen once they will never ... Read more
Product Details
Format
Hardback
Publication date
2014
Publisher
Springer Germany
Number of pages
429
Condition
New
Series
Epigenetics and Human Health
Number of Pages
416
Place of Publication
Berlin, Germany
ISBN
9783642451973
SKU
V9783642451973
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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