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Analysis and Purification Methods in Combinatorial Chemistry
Yan
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Description for Analysis and Purification Methods in Combinatorial Chemistry
Hardcover. Describes various analytical techniques and systems for the development, validation, quality control, purification, and physicochemical testing of combinatorial libraries. This book provides coverage of applications of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), and Fourier Transform Infrared (FTIR). Editor(s): Yan, Bing. Series: Chemical Analysis: A Series of Monographs on Analytical Chemistry and its Applications. Num Pages: 466 pages, Illustrations. BIC Classification: PBV; PDE; PNF. Category: (P) Professional & Vocational. Dimension: 229 x 160 x 27. Weight in Grams: 750.
Quality measurement, control, and improvement in combinatorial chemistry
Combinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are "purifiable," and "drugable."
To this end, Analysis and Purification Methods in Combinatorial Chemistry describes various analytical techniques and systems for the development, validation, quality control, purification, and physicochemical testing of combinatorial libraries. A new volume in Wiley's Chemical Analysis series, this text has four parts covering:
* Various approaches to monitoring reactions on solid support and optimizing reactions for library synthesis
* High-throughput analytical methods used to analyze the quality of libraries
* High-throughput purification techniques
* Analytical methods applied in post-synthesis and post-purification stages
Drawing from the contributions of respected experts in combinatorial chemistry, this comprehensive book provides coverage of applications of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), Fourier Transform Infrared (FTIR), micellar electrokinetic chromatography (MEKC) technologies, as well as other analytical techniques.
This eminently useful volume is an essential addition to the library of students and researchers studying or working in analytical chemistry, combinatorial chemistry, medicinal chemistry, organic chemistry, biotechnology, biochemistry, or biophysics.
Combinatorial chemistry has developed rapidly in the past decade, with great advances made by scientists working on analysis and purification of a large number of compounds and the analysis of polymer-bound compounds. However, formidable challenges lie ahead of today's researcher. For example, high-throughput analysis and purification technologies must be further developed to ensure combinatorial libraries are "purifiable," and "drugable."
To this end, Analysis and Purification Methods in Combinatorial Chemistry describes various analytical techniques and systems for the development, validation, quality control, purification, and physicochemical testing of combinatorial libraries. A new volume in Wiley's Chemical Analysis series, this text has four parts covering:
* Various approaches to monitoring reactions on solid support and optimizing reactions for library synthesis
* High-throughput analytical methods used to analyze the quality of libraries
* High-throughput purification techniques
* Analytical methods applied in post-synthesis and post-purification stages
Drawing from the contributions of respected experts in combinatorial chemistry, this comprehensive book provides coverage of applications of Nuclear Magnetic Resonance (NMR), liquid chromatography/mass spectrometry (LC/MS), Fourier Transform Infrared (FTIR), micellar electrokinetic chromatography (MEKC) technologies, as well as other analytical techniques.
This eminently useful volume is an essential addition to the library of students and researchers studying or working in analytical chemistry, combinatorial chemistry, medicinal chemistry, organic chemistry, biotechnology, biochemistry, or biophysics.
Product Details
Format
Hardback
Publication date
2003
Publisher
John Wiley and Sons Ltd United States
Number of pages
466
Condition
New
Series
Chemical Analysis: A Series of Monographs on Analytical Chemistry and its Applications
Number of Pages
496
Place of Publication
, United States
ISBN
9780471269298
SKU
V9780471269298
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About Yan
BING YAN, PhD, was born in China and received his PhD in chemistry at Columbia University in 1990. He then worked at Cambridge University and the University of Texas-Houston Medical School as a postdoctoral fellow. From 1993 to 1999, he worked for Novartis in the Core Technologies area of preclinical research in New Jersey. He is currently at the Discovery Chemistry division of Discovery Partners International, Inc., in San Francisco. His major research interests are drug discovery, optimization of solid-phase and solution-phase combinatorial synthesis, high-throughput quantitative and qualitative analysis, and high-throughput purification of combinatorial libraries. He has written four books and published over seventy reviews and research articles.
Reviews for Analysis and Purification Methods in Combinatorial Chemistry
"…a timely and valuable volume that would be an excellent addition to university libraries and the collections of individuals…" (E-STREAMS, February 2005) "...a useful book for chemists entering the field from either analytical or synthetic organic chemistry backgrounds.” (Angewandte Chemie International Edition, September 6, 2004) "This useful volume is a worthwhile addition to institute libraries as well as to the libraries students and researchers who are working in analytical chemistry, medicinal chemistry, organic chemistry, biotechnology…" (Energy Sources, August 2004)