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Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of Alpha-Aryl Ketones
Robert Doran
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Description for Asymmetric Synthesis of Bioactive Lactones and the Development of a Catalytic Asymmetric Synthesis of Alpha-Aryl Ketones
Paperback. Series: Springer Theses. Num Pages: 223 pages, 255 black & white illustrations, 3 colour illustrations, biography. BIC Classification: PNN; PNRD; PSB. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 12. Weight in Grams: 349.
This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereo control, which is significant because it allows the ... Read more
This thesis addresses two fundamental areas in contemporary organic chemistry: synthesis of natural products and catalytic asymmetric synthesis. Firstly, a new methodology, developed by our research group, which allows the asymmetric synthesis of lactones, a structural unit ubiquitous in natural products, was utilised in the synthesis of a number of natural product analogues that showed significant biological activity. Secondly, the development of a catalytic asymmetric synthesis of a key structural motif present in a number of natural products and pharmaceuticals was accomplished. During the course of this work we discovered dual stereo control, which is significant because it allows the ... Read more
Product Details
Format
Paperback
Publication date
2016
Publisher
Springer International Publishing AG Switzerland
Number of pages
223
Condition
New
Series
Springer Theses
Number of Pages
202
Place of Publication
Cham, Switzerland
ISBN
9783319370347
SKU
V9783319370347
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About Robert Doran
Robert, from Co. Wicklow, Ireland, graduated from University College Dublin in 2010 with a 1st class Honours BSc in Chemistry completing his final year project under the supervision of Professor Pat Guiry in the synthesis of aromatic Lipoxin analogues. He was awarded an Embark Postgraduate Scholarship from the Irish Research Council (IRC) in to undertake PhD studies with Professor Pat ... Read more
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