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Heinz Peter . Ed(S): Nasheuer - Genome Stability and Human Diseases - 9789400731257 - V9789400731257
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Genome Stability and Human Diseases

€ 238.15
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Description for Genome Stability and Human Diseases Paperback. This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research. Editor(s): Nasheuer, Heinz Peter. Series: Subcellular Biochemistry. Num Pages: 356 pages, biography. BIC Classification: MBGL; MFN; MJCL; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 19. Weight in Grams: 545.

Since the establishment of the DNA structure researchers have been highly interested in the molecular basis of the inheritance of genes and of genetic disorders. Scientific investigations of the last two decades have shown that, in addition to oncogenic viruses and signalling pathways alterations, genomic instability is important in the development of cancer. This view is supported by the findings that aneuploidy, which results from chromosome instability, is one of the hallmarks of cancer cells. Chromosomal instability also underpins our fundamental principles of understanding tumourigenesis: It thought that cancer arises from the sequential acquisition of genetic alterations in specific genes. ... Read more

This book is written by international leading scientists in the field of genome stability. Chapters are devoted to genome stability and anti-cancer drug targets, histone modifications, chromatin factors, DNA repair, apoptosis and many other key areas of research. The chapters give insights into the newest development of the genome stability and human diseases and bring the current understanding of the mechanisms leading to chromosome instability and their potential for clinical impact to the reader.

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Product Details

Format
Paperback
Publication date
2012
Publisher
Springer Netherlands
Number of pages
356
Condition
New
Series
Subcellular Biochemistry
Number of Pages
340
Place of Publication
Dordrecht, Netherlands
ISBN
9789400731257
SKU
V9789400731257
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

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