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Domenico Ribatti - History of Research on Tumor Angiogenesis - 9789048181568 - V9789048181568
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History of Research on Tumor Angiogenesis

€ 184.95
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Description for History of Research on Tumor Angiogenesis Paperback. In 1971, J. Folkman hypothesized that tumor growth is angiogenesis-dependent. In 2004, the FDA approved the first angiogenesis inhibitor. This book compiles the relevant literature of that history and emphasizes the antiangiogenic approach to treat tumors. Num Pages: 126 pages, biography. BIC Classification: MJCL; MMF; PDX; PSF. Category: (P) Professional & Vocational. Dimension: 234 x 156 x 7. Weight in Grams: 202.

In 1971, J. Folkman published in the “New England Journal of Medicine” a hypothesis that tumor growth is angiogenesis-dependent. Folkman introduced the concept that tumors probably secrete diffusible molecules that could stimulate the growth of new blood vessels toward the tumor and that the resulting tumor neovascularization could conceivably be prevented or interrupted by angiogenesis inhibitors. Solid and haematological tumors consist of an avascular and a subsequent vascular phase. Assuming that this depends on the release of angiogenic factors, acquisition of angiogenic capability can be seen as an expression of progression from neoplastic transformation to tumor growth and metastasis.

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This book offers a historical account of the relevant literature. It also emphasizes the crucial and paradigmatic role of angiogenesis as a biological process and the significance of antiangiogenic approach for the treatment of tumors.

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Product Details

Format
Paperback
Publication date
2010
Publisher
Springer Netherlands
Number of pages
126
Condition
New
Number of Pages
126
Place of Publication
Dordrecht, Netherlands
ISBN
9789048181568
SKU
V9789048181568
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

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