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. Ed(S): Balla, Tamas; Wymann, Matthias; York, John D. - Phosphoinositides II: the Diverse Biological Functions - 9789400730144 - V9789400730144
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Phosphoinositides II: the Diverse Biological Functions

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Description for Phosphoinositides II: the Diverse Biological Functions Hardback. Phosphoinositides play a major role in cellular signaling and membrane organization. Phosphatidylinositol(4,5)-bisphosphate is a prominent flag in the plasma membrane, while phosphatidylinositol-3-phosphate decorates early endosomes. This title deals with the role of phosphoinositides in membrane organization and vesicular traffic. Editor(s): Balla, Tamas; Wymann, Matthias; York, John D. Series: Subcellular Biochemistry. Num Pages: 476 pages, biography. BIC Classification: MFCC; PSF. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 30. Weight in Grams: 871.
Phosphoinositides play a major role in cellular signaling and membrane organization. During the last three decades we have learned that enzymes turning over phosphoinositides control vital physiological processes and are involved in the initiation and progression of cancer, inflammation, neurodegenerative, cardiovascular, metabolic disease and more. In two volumes, this book elucidates the crucial mechanisms that control the dynamics of phosphoinositide conversion. Starting out from phosphatidylinositol, a chain of lipid kinases collaborates to generate the oncogenic lipid phosphatidylinositol(3,4,5)-trisphosphate. For every phosphate group added, there are specific lipid kinases – and phosphatases to remove it. Additionally, phospholipases can cleave off the inositol ... Read more

Product Details

Format
Hardback
Publication date
2012
Publisher
Springer Netherlands
Number of pages
476
Condition
New
Series
Subcellular Biochemistry
Number of Pages
460
Place of Publication
Dordrecht, Netherlands
ISBN
9789400730144
SKU
V9789400730144
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

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