
Stock image for illustration purposes only - book cover, edition or condition may vary.
Description for Transcription Factors
Hardcover. This text aims to offer comprehensive coverage of current transcription factor data in the field of experimental haematology and transcription factor biology. Written by established experts in the field, it offers a presentation of cell lineage development. Editor(s): Ravid, Katya; Licht, Jonathan D. Num Pages: 640 pages, Illustrations. BIC Classification: MJF; PSF. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 187 x 34. Weight in Grams: 1324.
Transcription Factors
Normal and Malignant Development of Blood Cells
Katya Ravid and Jonathan Licht
The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias.
This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as:
* Transcription factors and the megakaryocytic, myeloid, and erythroid lineages
* Leukemias due to chromosomal translocations involving gene encoding transcription factors
* Oncogenesis and hematopoiesis
* In vivo studies of transcription factors implicated in hematopoiesis
* And much more
Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.
Normal and Malignant Development of Blood Cells
Katya Ravid and Jonathan Licht
The role of transcription factors in activating specific genes in blood cells is an important facet of hematopoiesis. Equally important, however, is the pursuit of genes rearranged and aberrantly activated in leukemias (blood malignancies). Transcription Factors: Normal and Malignant Development of Blood Cells focuses on those major transcription factors involved in activation of lineage-specific gene expression during normal versus malignant development of specific blood lineages, as revealed from gene promoter studies, knockout of transcription factors in mice models, and the identification and characterization of chromosomal rearrangement in human blood leukemias.
This complete digest of current transcription factor data offers comprehensive coverage of the myriad of transcription factors in blood cell development, composed by established experts in the field. In addition to updating the reader on the connection between chromosomal translocations involving transcription factors and cellular transformation leading to leukemia, Transcription Factors also reviews such subjects as:
* Transcription factors and the megakaryocytic, myeloid, and erythroid lineages
* Leukemias due to chromosomal translocations involving gene encoding transcription factors
* Oncogenesis and hematopoiesis
* In vivo studies of transcription factors implicated in hematopoiesis
* And much more
Appealing to both the researcher and the clinician in the field of hematology, Transcription Factors is a timely presentation of cell lineage development and sheds light on the processes involved in the development of specific leukemias. Providing insight into the study of transcription factors, readers will gain an understanding of mechanisms that lead to normal lineage commitment and terminal differentiation.
Product Details
Format
Hardback
Publication date
2000
Publisher
John Wiley and Sons Ltd United States
Number of pages
640
Condition
New
Number of Pages
640
Place of Publication
New York, United States
ISBN
9780471350545
SKU
V9780471350545
Shipping Time
Usually ships in 7 to 11 working days
Ref
99-1
About Ravid
Katya Ravid is the editor of Transcription Factors: Normal and Malignant Development of Blood Cells, published by Wiley. Jonathan D. Licht is the editor of Transcription Factors: Normal and Malignant Development of Blood Cells, published by Wiley.
Reviews for Transcription Factors
"The researchers who work actively on these issues will find this book to be a source of discussion and references." (International Journal of Hematology, October 2001)