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Arber, W.; Henle, W.; Hofschneider, P. H.; Humphrey, J. H.; Klein, J.; Koldovsky, P.; Koprowski, H.; Maaloe, O.; Melchers, F.; Rott, R. - Current Topics in Microbiology and Immunology - 9783642666551 - V9783642666551
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Current Topics in Microbiology and Immunology

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Description for Current Topics in Microbiology and Immunology Paperback. Series: Current Topics in Microbiology and Immunology. Num Pages: 220 pages, biography. BIC Classification: MBGR; PSA. Category: (P) Professional & Vocational. Dimension: 244 x 170 x 12. Weight in Grams: 394.
Immunoglobulin gene expression appears to include a number of unique features (Cohn, 1971; Gaily and Edelman, 1972; Hood et aI. , 1975). First, a variety of genetic and protein structural evidence suggests that two discrete genes - both a variable region gene and a constant region gene - specify each heavy chain and each light chain. This constitutes the twogene-one polypeptide hypothesis. Second, a single differentiated lymphocyte or plasma cell appears to express only one heavy chain allele and one light chain allele at a time. This is the only example of allelic exclusion known in mammalian cells except for ... Read more

Product Details

Format
Paperback
Publication date
2011
Publisher
Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Germany
Number of pages
220
Condition
New
Series
Current Topics in Microbiology and Immunology
Number of Pages
216
Place of Publication
Berlin, Germany
ISBN
9783642666551
SKU
V9783642666551
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

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