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Disordered Vertebral and Rib Morphology in Pudgy Mice
Frederic Shapiro
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Description for Disordered Vertebral and Rib Morphology in Pudgy Mice
Paperback. Series: Advances in Anatomy, Embryology and Cell Biology. Num Pages: 132 pages, 5 black & white illustrations, 15 colour illustrations, biography. BIC Classification: MFN; PSVL. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 7. Weight in Grams: 221.
This book presents results obtained from the whole mount preparations, radiological, and histological studies of 60 pu/pu and pu/+ mice from late embryo until 3 months of age. Most mice were in the embryo to 6 week age group where vertebral developmental changes are most marked. Although vertebral abnormalities have been identified as due to mutations in the delta-like 3 (Dll3) gene, it is evident that each mouse has differing structural abnormalities. The disorder is analogous to human congenital scoliosis, a common variant of which is spondylocostal dysplasia. The histological studies presented in this book include plastic embedded sections which allow for ... Read more
This book presents results obtained from the whole mount preparations, radiological, and histological studies of 60 pu/pu and pu/+ mice from late embryo until 3 months of age. Most mice were in the embryo to 6 week age group where vertebral developmental changes are most marked. Although vertebral abnormalities have been identified as due to mutations in the delta-like 3 (Dll3) gene, it is evident that each mouse has differing structural abnormalities. The disorder is analogous to human congenital scoliosis, a common variant of which is spondylocostal dysplasia. The histological studies presented in this book include plastic embedded sections which allow for ... Read more
Product Details
Format
Paperback
Publication date
2016
Publisher
Springer International Publishing AG Switzerland
Number of pages
132
Condition
New
Series
Advances in Anatomy, Embryology and Cell Biology
Number of Pages
123
Place of Publication
Cham, Switzerland
ISBN
9783319431499
SKU
V9783319431499
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About Frederic Shapiro
Frederic Shapiro received his MD degree from the University of Toronto Faculty of Medicine. He completed a residency in orthopedic surgery at the Montreal General Hospital: McGill University, Montreal, Quebec and a research fellowship in orthopedic surgery at Boston Children's Hospital.Frederic Shapiro, MD, Orthopedic Research Laboratory, Children's Hospital, Boston, USA.
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