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G Protein-Coupled Receptors - Modeling and Simulation
Marta . Ed(S): Filizola
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Description for G Protein-Coupled Receptors - Modeling and Simulation
Hardback. Editor(s): Filizola, Marta. Series: Advances in Experimental Medicine and Biology. Num Pages: 228 pages, 14 black & white illustrations, 45 colour illustrations, 25 black & white tables, biograp. BIC Classification: MFN; PBW; PSBC. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 18. Weight in Grams: 661.
G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses. Since GPCRs are natural targets for approximately 40% of all modern medicines, it is not surprising that they have been the subject of intense research. Notwithstanding the amount of data generated over the years, discovering ligands of these receptors with optimal therapeutic properties is not straightforward and has certainly been hampered for years by the lack of high-resolution structural information about these receptors. Luckily, there has been a steady increase of high-resolution crystal structures of these receptors since 2007, and ... Read more
G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses. Since GPCRs are natural targets for approximately 40% of all modern medicines, it is not surprising that they have been the subject of intense research. Notwithstanding the amount of data generated over the years, discovering ligands of these receptors with optimal therapeutic properties is not straightforward and has certainly been hampered for years by the lack of high-resolution structural information about these receptors. Luckily, there has been a steady increase of high-resolution crystal structures of these receptors since 2007, and ... Read more
Product Details
Format
Hardback
Publication date
2013
Publisher
Springer Netherlands
Number of pages
228
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
228
Place of Publication
Dordrecht, Netherlands
ISBN
9789400774223
SKU
V9789400774223
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
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