.png){kind=logo}
Stock image for illustration purposes only - book cover, edition or condition may vary.
Gamma-Glutamyl Transpeptidases: Structure and Function
Castellano, Immacolata; Merlino, Antonello
€ 71.77
FREE Delivery in Ireland
Description for Gamma-Glutamyl Transpeptidases: Structure and Function
paperback. Series: SpringerBriefs in Biochemistry and Molecular Biology. Num Pages: 57 pages, 10 black & white illustrations, 18 colour illustrations, biography. BIC Classification: MFG; PSBZ. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 8. Weight in Grams: 124.
Gamma-Glutamyl Transpeptidases (γ-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the γ-glutamyl amide bond of glutathione to liberate cysteinylglycine. The released γ-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptides (transpeptidation). γ-GT plays a key role in the gamma glutamyl cycle by regulating the cellular levels of the antioxidant glutathione, hence it is a critical enzyme in maintaining cellular redox homeostasis.γ-GT is upregulated during inflammation and in several human tumors, and it is involved in many physiological disorders related to oxidative stress, such as Parkinson’s disease and diabetes. Furthermore, this ... Read more
Gamma-Glutamyl Transpeptidases (γ-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the γ-glutamyl amide bond of glutathione to liberate cysteinylglycine. The released γ-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short peptides (transpeptidation). γ-GT plays a key role in the gamma glutamyl cycle by regulating the cellular levels of the antioxidant glutathione, hence it is a critical enzyme in maintaining cellular redox homeostasis.γ-GT is upregulated during inflammation and in several human tumors, and it is involved in many physiological disorders related to oxidative stress, such as Parkinson’s disease and diabetes. Furthermore, this ... Read more
Product Details
Format
Paperback
Publication date
2013
Publisher
Springer Switzerland
Number of pages
57
Condition
New
Series
SpringerBriefs in Biochemistry and Molecular Biology
Number of Pages
57
Place of Publication
, Switzerland
ISBN
9783034806817
SKU
V9783034806817
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Gamma-Glutamyl Transpeptidases: Structure and Function