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Gene Targeting Protocols
Eric B. Kmiec
€ 192.31
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Description for Gene Targeting Protocols
Hardback. This volume provides basic and advanced protocols for targeting the genomic/chromosomal level. These protocols are aimed at improving gene selection and specificity, and are written in a convenient step-by-step fashion. Series: Methods in Molecular Biology. Num Pages: 233 pages, biography. BIC Classification: PSAK; TCBG. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 19. Weight in Grams: 559.
The potential now exists in many experimental systems to transfer a cloned, modified gene back into the genome of the host organism. In the ideal situation, the cloned gene is returned to its homologous location in the genome and becomes inserted at the target locus. This process is a controlled means for the repair of DNA damage and ensures accurate chromosome disjunction during meiosis. The paradigm for thinking about the mechanism of this p- cess has emerged primarily from two sources: (1) The principles of reaction mechanics have come from detailed biochemical analyses of the RecA protein purified from Escherichia ... Read more
The potential now exists in many experimental systems to transfer a cloned, modified gene back into the genome of the host organism. In the ideal situation, the cloned gene is returned to its homologous location in the genome and becomes inserted at the target locus. This process is a controlled means for the repair of DNA damage and ensures accurate chromosome disjunction during meiosis. The paradigm for thinking about the mechanism of this p- cess has emerged primarily from two sources: (1) The principles of reaction mechanics have come from detailed biochemical analyses of the RecA protein purified from Escherichia ... Read more
Product Details
Format
Hardback
Publication date
1999
Publisher
Humana Press Inc. United States
Number of pages
233
Condition
New
Series
Methods in Molecular Biology
Number of Pages
233
Place of Publication
Totowa, NJ, United States
ISBN
9780896033603
SKU
V9780896033603
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
Reviews for Gene Targeting Protocols
"The book also has several techniques for using oligonucleotides in gene targeting, a methodology that may well revolutionize the entire field." - Cellular and Molecular Biology