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. Ed(S): Gullberg, Donald (Uppsala University, Sweden) - I Domain Integrins - 9789401791526 - V9789401791526
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I Domain Integrins

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Description for I Domain Integrins Hardback. Editor(s): Gullberg, Donald (Uppsala University, Sweden). Series: Advances in Experimental Medicine and Biology. Num Pages: 193 pages, 18 black & white illustrations, 32 colour illustrations, biography. BIC Classification: MBGR; MFN; PSA; PSB. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 13. Weight in Grams: 576.

The integrin family is composed of 24 members and approximately ten years ago (2003) we published a book devoted to the nine I domain integrin subunits. In this second edition, I am pleased that most of the original authors have been able to contribute to the updated version.

I domain containing integrins include collagen receptors and leukocyte receptors. In 2003 the knockout mouse phenotypes for all of the I domain integrins had not yet been published; they are now, and are summarized and discussed in this edition.

Interestingly, a recent 10 integrin mutation in dogs has indicated that collagen-binding integrins in the ... Read more

In the cancer field, the microenvironment is taking center stage, and here collagen receptors on fibroblasts are predicted to play important roles in paracrine signaling, in regulating tissue stiffness and matrix remodeling.

New technologies, new mouse models in combination with analyses of I integrins in larger animals/humans are thus predicted to increase our knowledge about this group of receptors. With this in mind we look forward to another 10 years of research with I domain integrins.

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Product Details

Format
Hardback
Publication date
2014
Publisher
Springer Netherlands
Number of pages
193
Condition
New
Series
Advances in Experimental Medicine and Biology
Number of Pages
179
Place of Publication
Dordrecht, Netherlands
ISBN
9789401791526
SKU
V9789401791526
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15

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