Induced Pluripotent Stem Cells in Brain Diseases
Heine, Vivi M.; Dooves, Stephanie; Holmes, Dwayne; Wagner, Judith
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Description for Induced Pluripotent Stem Cells in Brain Diseases
Paperback. This book describes a breakthrough approach in which somatic cells are reprogrammed into induced pluripotent (iPS) cells. Covers reprogramming methods, control and determination of cell identity, new epigenetic models and iPS cell therapy in brain disease. Series: Springerbriefs in Neuroscience. Num Pages: 74 pages, 1 black & white illustrations, 6 colour illustrations. BIC Classification: MFN; MJN; PSAN. Category: (P) Professional & Vocational. Dimension: 153 x 239 x 6. Weight in Grams: 134.
Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic “memories” of what they were that can affect reprogramming. This book discusses the various methods to ... Read more
Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic “memories” of what they were that can affect reprogramming. This book discusses the various methods to ... Read more
Product Details
Format
Paperback
Publication date
2011
Publisher
Springer Netherlands
Number of pages
74
Condition
New
Series
Springerbriefs in Neuroscience
Number of Pages
59
Place of Publication
Dordrecht, Netherlands
ISBN
9789400728158
SKU
V9789400728158
Shipping Time
Usually ships in 15 to 20 working days
Ref
99-15
About Heine, Vivi M.; Dooves, Stephanie; Holmes, Dwayne; Wagner, Judith
Dr. Vivi M. Heine is an assistant professor in the Department of Pediatrics of the VU University Medical Center in Amsterdam, Netherlands. Dr. Heine earned her doctoral degree in Neurobiology from the University of Amsterdam, Netherlands. She then received post-doctoral training at the Dana Farber Cancer Institute, Harvard University, Boston and at the Eli and Edythe Broad Center of Regenerative ... Read more
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